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What is Ketamine?
Ketamine (brand name Ketalar) is a dissociative anesthetic (blocks sensory perception) that has been available by prescription in the U.S. ketamine drug, since the 1970s for human and veterinary uses. Dissociative drugs can lead to distortion of sights, colors, sounds, self, and one’s environment. ketamine clinic, It is available in a clear liquid or off-white powder form for intravenous injection. ketamine depression treatment, Other dissociative drugs include phencyclidine (PCP) and dextromethorphan (DXM)
- Ketamine can provide pain relief and short-term memory loss (for example, amnesia of a medical procedure).
- In surgery, it is used an induction and maintenance agent for sedation and to provide general anesthesia.
- It has also been used for pain control in burn therapy, ketamine side effects, battlefield injuries, and in children who cannot use other anesthetics due to side effects or allergies.
- This drug is also under research and holding promise as a treatment for severe depression in difficult cases.
- It is often preferred as an anesthetic due to a lower chance for depressed breathing, as often occurs with opioids. Buy Legal Ketamine Online
Pharmacology of Ketamine
Pharmacologically, ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, but at higher doses may also bind to the opioid mu and sigma receptors. ketamine definition, This drug disrupts the neurotransmitter (brain chemical) glutamate. Glutamate is involved with learning, memory, emotion, pain recognition. ketamine clinic, It can exhibit sympathomimetic activity which can lead to rapid heart rate and elevated blood pressure.
It is related to phencyclidine (PCP), but has less than 10% of the potency of pure PCP.
This agent is a lipid soluble compound, has an initial rapid distribution and large volume of distribution, with a half-life of 10 to 15 minutes. ketamine and depression, ketamine for pain, Secondarily, ketamine treatment, the drug distributes into peripheral tissues with a slower elimination half-life of up to 3 hours, undergoes hepatic metabolism and is excreted in the urine
Ketamine, categorized as a “dissociative anesthetic,”1 is used in powdered or liquid form as an anesthetic, usually on animals. It can be injected, consumed in drinks, snorted, or added to joints or cigarettes. Ketamine was placed on the list of controlled substances in the US in 1999.
Short- and long-term effects include increased heart rate and blood pressure, nausea, vomiting, numbness, depression, amnesia, hallucinations, and potentially fatal respiratory problems. Ketamine users can also develop cravings for the drug. At high doses, users experience an effect referred to as “K-Hole,” an “out of body” or “near-death” experience.
Due to the detached, dreamlike state it creates, where the user finds it difficult to move, ketamine has been used as a “date-rape” drug.
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